CAV1 polyclonal antibody
产品名称： CAV1 polyclonal antibody
英文名称： CAV1 polyclonal antibody
产品编号： PAB11899
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CAV1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus of human CAV1.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 22
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 857
- Gene Name:
- CAV1
- Gene Alias:
- BSCL3,CAV,CGL3,MSTP085,VIP21
- Gene Description:
- caveolin 1, caveolae protein, 22kDa
- Omim ID:
- 601047
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000025031,caveolae protein, 22-kD,caveolin 1,caveolin 1 caveolae protein, 22kD,caveolin 1, alpha isoform,caveolin 1, beta isoform,caveolin-1 beta isoform protein,cell growth-inhibiting protein 32
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anoxia
- Arrhythmias, Cardiac
- Atherosclerosis
- Atrial Fibrillation
- Atrioventricular Block
- Breast Neoplasms
- Calcinosis
- Carcinoma
- Cardiovascular Diseases
- Colorectal Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Edema
- Fibrosis
- Genetic Predisposition to Disease