Anti-CTCF Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-CTCF Polyclonal Antibody

Anti-CTCF Polyclonal Antibody

商家询价

产品名称: Anti-CTCF Polyclonal Antibody

英文名称: Anti-CTCF Polyclonal Antibody

产品编号: K002202P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-01-14T14:04:38

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北京索莱宝科技有限公司
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Anti-CTCF Polyclonal Antibody

品牌:solarbio | 货号:K002202P
商品货号:商品品牌:规格基本售价:选择规格
K002202P-50ulsolarbio50ul960.00元
K002202P-100ulsolarbio100ul1600.00元
英文名称Anti-CTCF Polyclonal Antibody
别名MRD21
应用WB IF IP ChIP
稀释比例WB 1:500-2000. IF 1:50-200. IP 1:50-100. ChIP 1:50-200.
交叉反应Human Mouse Rat Monkey
蛋白分子量83kDa
Gene ID10664
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CTCF
性状液体
Public Immunogen RangeRecombinant protein of human CTCF
Subcellular LocationsChromosome Nucleus centromere nucleoplasm
Swiss ProtP49711
克隆类型Polyclonal Antibody
背景资料This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.