SPAG6 monoclonal antibody (M01), clone 3E3
产品名称： SPAG6 monoclonal antibody (M01), clone 3E3
英文名称： SPAG6 monoclonal antibody (M01), clone 3E3
产品编号： H00009576-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SPAG6.
- Immunogen:
- SPAG6 (NP_036575, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYK*
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG3 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- SPAG6 monoclonal antibody (M01), clone 3E3 Western Blot analysis of SPAG6 expression in A-431 ( Cat # L015V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 9576
- GeneBank Accession#:
- NM_012443
- Protein Accession#:
- NP_036575
- Gene Name:
- SPAG6
- Gene Alias:
- DKFZp434I153,MGC26276,Repro-SA-1,pf16
- Gene Description:
- sperm associated antigen 6
- Omim ID:
- 605730
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019296,OTTHUMP00000019297,axoneme central apparatus protein,sperm flagellar protein
- Related Disease