PGR monoclonal antibody, clone hPRa2+hPRa3
产品名称： PGR monoclonal antibody, clone hPRa2+hPRa3
英文名称： PGR monoclonal antibody, clone hPRa2+hPRa3
产品编号： MAB1975
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native PGR.
- Immunogen:
- Native purified human PGR.
- Host:
- Mouse
- Reactivity:
- Horse, Human, Pig
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Native Purified Protein.
- Recommend Usage:
- Western blot (1 ug/mL)
Immunoprecipitation (2 ug/mg of protein lysate)
Immunohistochemistry on frozen and formalin to fixed/paraffin to embedded tissues (2 to 4 ug/mL)
The optimal working dilution should be determined by the end
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Development of a preclinical model for hormonal therapy of human endometrial carcinomas.
Satyaswaroop PG.Ann Med. 1993 Apr;25(2):105-11.
- 2.
- Relationship between 90-kilodalton heat shock protein, estrogen receptor, and progesterone receptor in human mammary tumors.
Shyamala G, Schweitzer M, Ullrich SJ.Breast Cancer Res Treat. 1993;26(1):95-100.
- 3.
- Apparent resistance in human endometrial carcinoma during combination treatment with tamoxifen and progestin may result from desensitization following downregulation of tumor progesterone receptor.
Satyaswaroop PG, Clarke CL, Zaino RJ, Mortel R.Cancer Lett. 1992 Feb 29;62(2):107-14.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- Immunoprecipitation
- Entrez GeneID:
- 5241
- Gene Name:
- PGR
- Gene Alias:
- NR3C3,PR
- Gene Description:
- progesterone receptor
- Omim ID:
- 607311
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Adenocarcinoma
- Adenocarcinoma, Clear Cell
- Adhesions
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Carcinoma, Endometrioid
- Carcinoma, Lobular
- Cardiovascular Diseases
- Colorectal Neoplasms
- Connective Tissue Diseases
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Endometrial Neoplasms