Anti-MET Polyclonal Antibody

K001568P-50ul	Solarbio	50ul	960.00元
K001568P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit MET Polyclonal Antibody
应用2	WB
克隆类型2	Polyclonal Antibody
别名	AUTS9;DFNB97;HGFR;RCCP2;c-Met
应用	WB
稀释比例	WB1:500-1:2000
交叉反应	Human
蛋白分子量	156kDa
Gene ID	4233
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human MET
性状	Lyophilized or Liquid
Swiss Prot	P08581
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.