CXCR1 polyclonal antibody
产品名称： CXCR1 polyclonal antibody
英文名称： CXCR1 polyclonal antibody
产品编号： PAB8941
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CXCR1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 13-30 of human CXCR1.
- Sequence:
- DDLNFTGNPPADEDYSPC
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In buffer containing 0.02% sodium azide
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500)
Immunoprecipitation (1:250)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Chemokine receptors: signposts to brain development and disease.
Tran PB, Miller RJ.Nat Rev Neurosci. 2003 Jun;4(6):444-55.
- 2.
- Interleukin-8 secreted by endothelial cells induces chemotaxis of melanoma cells through the chemokine receptor CXCR1.
Ramjeesingh R, Leung R, Siu CH.FASEB J. 2003 Jul;17(10):1292-4. Epub 2003 May 8.
- 3.
- The role of chemokines and chemokine receptors in progressive renal diseases.
Segerer S.Am J Kidney Dis. 2003 Mar;41(3 Suppl 1):S15-8.
- Application Image
- Western Blot (Recombinant protein)
- enlarge
- Immunohistochemistry
- Immunoprecipitation
- Entrez GeneID:
- 3577
- Gene Name:
- CXCR1
- Gene Alias:
- C-C,C-C-CKR-1,CD128,CD181,CDw128a,CKR-1,CMKAR1,IL8R1,IL8RA,IL8RBA
- Gene Description:
- chemokine (C-X-C motif) receptor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
- Other Designations:
- receptor,alpha,interleukin-8 receptor type 1,interleukin-8 receptor type A
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